Role of mutation in the gyrA and parC genes of nalidixic-acid-resistant salmonella serotypes isolated from animals in the United Kingdom.

doi:10.1093/jac/41.6.635

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Article

Role of mutation in the gyrA and parC genes of nalidixic-acid-resistant salmonella serotypes isolated from animals in the United Kingdom.

The Journal of antimicrobial chemotherapy - 1 Jun 1998

Piddock L J, Ricci V, McLaren I, Griggs D J

Abstract excerpt

To answer the question as to whether isolates of salmonella from animals with decreased susceptibility to quinolones possess the same mechanism of resistance as isolates from humans, the polymerase chain reaction (PCR) was used to amplify a 347 base pair fragment equivalent to codons 39-159 cover...

Topics

Animals
Anti-Infective Agents
DNA Gyrase
DNA Topoisomerase IV
DNA Topoisomerases, Type II
DNA, Bacterial
Drug Resistance, Microbial
Microbial Sensitivity Tests
Mutation
Nalidixic Acid
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Salmonella
Salmonella Infections, Animal
Serotyping
United Kingdom

Source

Open in PubMed

Identifiers

PMID: 9687102
DOI: 10.1093/jac/41.6.635

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9687102-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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