Article
Two distinct forms of soluble MHC class I molecules synthesized by different mechanisms in normal rat cells in vitro.
Human immunology - 1 Jul 1998
Zhai Y, Knechtle S
Abstract excerpt
Rat soluble MHC class I synthesis was studied at both RNA and protein levels to determine whether multiple forms of soluble MHC class I molecules are produced by different mechanisms. RT-PCR and sequencing of MHC class I transcripts identified an alternatively spliced nonclassical MHC class I gen...
Topics
- Alleles
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- Histocompatibility Antigens
- Histocompatibility Antigens Class I
- Hydrolysis
- Liver
- Male
- Metalloendopeptidases
- Molecular Sequence Data
- Rats
- Rats, Inbred ACI
- Rats, Inbred Lew
- Solubility
- Spleen
- Transcription, Genetic