Article
Two distinct forms of soluble MHC class I molecules synthesized by different mechanisms in normal rat cells in vitro.
Human immunology - 1 Jul 1998
Zhai Y, Knechtle S
Abstract excerpt
Rat soluble MHC class I synthesis was studied at both RNA and protein levels to determine whether multiple forms of soluble MHC class I molecules are produced by different mechanisms. RT-PCR and sequencing of MHC class I transcripts identified an alternatively spliced nonclassical MHC class I gene product, lacking both exon 5 and 6, in both spleen and liver. Immunoprecipitation and SDS-PAGE identified two...
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