Article
Familial renal oncocytoma: clinicopathological study of 5 families.
The Journal of urology - 1 Aug 1998
Weirich G, Glenn G, Junker K, Merino M, Störkel S, Lubensky I, Choyke P, Pack S, Amin M, Walther M M, Linehan W M, Zbar B
Abstract excerpt
PURPOSE: We analyzed familial renal oncocytoma to provide a foundation for studies aimed at defining genes involved in the pathogenesis of renal oncocytoma. MATERIALS AND METHODS: We describe 5 families with multiple members affected with renal oncocytoma. Tumors were analyzed pathologically, and...
Topics
- Adenoma, Oxyphilic
- Adult
- Aged
- Aged, 80 and over
- Blotting, Southern
- Child
- DNA, Neoplasm
- Diseases in Twins
- Female
- Genes, Tumor Suppressor
- Humans
- Kidney Neoplasms
- Male
- Middle Aged
- Mutation
- Oncogenes
- Pedigree
- Proto-Oncogenes
