Article
Waiting with and without recombination: the time to production of a double mutant.
Theoretical population biology - 1 Jun 1998
Christiansen F B, Otto S P, Bergman A, Feldman M W
Abstract excerpt
R.A. Fisher and H.J. Muller argued in the 1930s that a major evolutionary advantage of recombination is that it allows favorable mutations to be combined within an individual even when they first appear in different individuals. This effect is evaluated in a two-locus, two-allele model by calcula...
Topics
- Biological Evolution
- Gene Frequency
- Genotype
- Humans
- Models, Genetic
- Monte Carlo Method
- Mutation
- Population Density
- Recombination, Genetic
- Selection, Genetic
- Stochastic Processes
- Time Factors