Article
Waiting with and without recombination: the time to production of a double mutant.
Theoretical population biology - 1 Jun 1998
Christiansen F B, Otto S P, Bergman A, Feldman M W
Abstract excerpt
R.A. Fisher and H.J. Muller argued in the 1930s that a major evolutionary advantage of recombination is that it allows favorable mutations to be combined within an individual even when they first appear in different individuals. This effect is evaluated in a two-locus, two-allele model by calculating the average waiting time until a new genotypic combination first appears in a haploid population. Three...
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