Article
The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases.
The Journal of biological chemistry - 31 Jul 1998
Nagiec M M, Skrzypek M, Nagiec E E, Lester R L, Dickson R C
Abstract excerpt
Sphingolipid long chain bases (LCBs) and phosphorylated derivatives, particularly sphingosine 1-phosphate, are putative signaling molecules. To help elucidate the physiological roles of LCB phosphates, we identified two Saccharomyces cerevisiae genes, LCB4 (YOR171c) and LCB5 (YLR260w), which enco...
Topics
- Amino Acid Sequence
- Fungal Proteins
- Genes, Fungal
- Kinetics
- Lysophospholipids
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Phosphorylation
- Phosphotransferases
- Phosphotransferases (Alcohol Group Acceptor)
- Recombinant Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Alignment
- Sphingolipids
- Sphingosine
- Substrate Specificity