Article
Polymorphisms of the calcitonin receptor gene are associated with bone mineral density in postmenopausal Italian women.
Biochemical and biophysical research communications - 9 Jul 1998
Masi L, Becherini L, Colli E, Gennari L, Mansani R, Falchetti A, Becorpi A M, Cepollaro C, Gonnelli S, Tanini A, Brandi M L
Abstract excerpt
Recognition of a major genetic component in bone mass determination represented the basis for studies aiming to the identification of underlying major and minor genes. Bone mineral density (BMD) represents the continuous trait to be quantified in order to evaluate segregation of candidate genes with risk of osteoporosis. Polymorphisms at the vitamin D receptor (VDR), estrogen receptor, (ER), collagen type I, and...
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