Article
Association of low bone mass with vitamin d receptor gene and calcitonin receptor gene polymorphisms in juvenile idiopathic arthritis.
The Journal of rheumatology - 1 Oct 2002
Masi Laura, Cimaz Rolando, Simonini Gabriele, Bindi Giuseppe, Stagi Stefano, Gozzini Alessia, Malentacchi Cecilia, Brandi Maria Luisa, Falcini Fernanda
Abstract excerpt
OBJECTIVE: To compare bone density with polymorphisms in the calcitonin receptor (CTR) and vitamin D receptor (VDR) genes in 50 patients with juvenile idiopathic arthritis and 80 matched controls. METHODS: Bone mineral density (BMD) was measured by dual energy x-ray absorptiometry at the lumbar spine. Genomic DNA was isolated from EDTA blood samples by standard procedures. Polymerase chain reaction was performed...
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