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Article

Effects of Gonadal Steroids and Their Antagonists on DNA Synthesis in Human Vascular Cells

1 Jul 1998

Abstract excerpt

The cardiovascular effect of estrogen is currently under intense investigation, but the role of androgens in vascular biology has attracted little attention. Because endothelial repair and vascular smooth muscle cell (VSMC) proliferation affect atherogenesis, we analyzed the effects of 17beta-estradiol (E2), dihydrotestosterone (DHT), and sex hormone antagonists on DNA synthesis in human umbilical VSMCs and in...

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PMID: 9674635
DOI: 10.1161/01.hyp.32.1.39

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