Article
Association of HLA class-II genes and anti-neutrophil cytoplasmic antibodies in Chinese patients with inflammatory bowel disease.
Scandinavian journal of gastroenterology - 1 Jun 1998
Lee Y T, Sung J J, Poon P, Lai K N, Li P K
Abstract excerpt
BACKGROUND: Inflammatory bowel disease is common in the West but rare in China. The genetic factor predisposing to the disease is unclear. Ulcerative colitis (UC) is found to be associated with HLA DR2 alleles in the West. Subgroups of UC patients have been further defined by the presence of anti...
Topics
- Adult
- Antibodies, Antineutrophil Cytoplasmic
- Case-Control Studies
- Colitis, Ulcerative
- Female
- Fluorescent Antibody Technique, Indirect
- Gene Frequency
- Genes, MHC Class II
- Genotype
- Hong Kong
- Humans
- Male
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length