Article
Obesity genes: molecular genetic approaches to drug target identification.
Farmaco (Societa chimica italiana : 1989) - 1 Apr 1998
Grippo J F, Burn P
Abstract excerpt
The environment for developing novel therapeutic agents has undergone dramatic change over the past decade. Innovative strategies for identifying and utilizing molecular targets linked to particular human diseases are replacing the classic approach of screening chemical compounds for potential therapeutic action on unknown targets. Since genetic components are involved in many known diseases, mouse and human...
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