Article
The L1 major capsid protein of human papillomavirus type 16 variants affects yield of virus-like particles produced in an insect cell expression system.
Journal of clinical microbiology - 1 Jul 1998
Touze A, El Mehdaoui S, Sizaret P Y, Mougin C, Muñoz N, Coursaget P
Abstract excerpt
The L1 major capsid proteins of six human papillomavirus type 16 (HPV-16) strains were expressed in insect cells by using recombinant baculoviruses. Virus-like particles (VLPs) which appeared similar to empty virions were identified by electron microscopy for all HPV strains investigated. However...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Viral
- Capsid
- Capsid Proteins
- Cell Line
- DNA
- Enzyme-Linked Immunosorbent Assay
- Female
- Genes, Viral
- Genetic Variation
- Humans
- Immunoglobulin G
- Insecta
- Microscopy, Electron