Article
Type IV pili, transient bacterial aggregates, and virulence of enteropathogenic Escherichia coli.
Science (New York, N.Y.) - 26 Jun 1998
Bieber D, Ramer S W, Wu C Y, Murray W J, Tobe T, Fernandez R, Schoolnik G K
Abstract excerpt
Type IV bundle-forming pili of enteropathogenic Escherichia coli are required for the localized adherence and autoaggregation phenotypes. Whether these pili are also required for virulence was tested in volunteers by inactivating bfpA or bfpT (perA) encoding, respectively, the pilus subunit and t...
Topics
- Adolescent
- Adult
- Agglutination
- Bacterial Adhesion
- Cell Membrane
- Diarrhea
- Epithelial Cells
- Escherichia coli
- Escherichia coli Infections
- Fimbriae, Bacterial
- Humans
- Intestinal Mucosa
- Middle Aged
- Mutation
- Operon
- Phenotype
- Tumor Cells, Cultured
- Virulence