Article
BfpU, a soluble protein essential for type IV pilus biogenesis in enteropathogenic Escherichia coli.
Microbiology (Reading, England) - 1 Aug 2002
Schreiber Wiebke, Stone Kelly D, Strong Margaret A, DeTolla Louis J, Hoppert Michael, Donnenberg Michael S
Abstract excerpt
A cluster of 14 genes located on the large plasmid of enteropathogenic Escherichia coli (EPEC) strains is sufficient to direct the biogenesis of the type IV bundle-forming pilus (BFP) in a recombinant E. coli host. The fifth gene in the cluster, bfpU, encodes a protein that is predicted to be localized to the periplasmic space. To determine whether BfpU is necessary for pilus biogenesis, the authors constructed a...
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