Article
Angiotensin I-converting enzyme and angiotensinogen gene interaction and prediction of essential hypertension.
Kidney international - 1 Jun 1998
Vasků A, Soucek M, Znojil V, Rihácek I, Tschöplová S, Strelcová L, Cídl K, Blazková M, Hájek D, Hollá L, Vácha J
Abstract excerpt
To prove whether the interaction between insertion/deletion (I/D) angiotensin I converting enzyme (ACE) and M235T angiotensinogen (AGT) gene polymorphic alleles could contribute to causing essential hypertension, we examined subjects from the Czech Republic (365 Caucasians total; 202 normotensives and 163 hypertensives). Subjects were genotyped for insertion/deletion polymorphism of ACE (I/D ACE, intron 16) and...
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