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Article

Disruption of PML-associated nuclear bodies mediated by the human cytomegalovirus major immediate early gene product.

1 May 1998

Abstract excerpt

The PML gene product is associated with a defined nuclear structure (10-20 per cell) known variously as PML-bodies, ND10, PODs or Kr bodies. Certain conditions are known to compromise the integrity of PML-bodies; these include environmental stress (e.g. heat shock), a chromosomal translocation-associated acute promyelocytic leukaemia, and infection with certain viruses [including human cytomegalovirus (HCMV),...

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PMID: 9603339
DOI: 10.1099/0022-1317-79-5-1233

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