A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state.

Abstract excerpt

There is now substantial evidence that Borrelia burgdorferi, the Lyme disease spirochete, undergoes major alterations in antigenic composition as it cycles between its arthropod and mammalian hosts. In this report, we cultivated B. burgdorferi 297 within dialysis membrane chambers implanted into the peritoneal cavities of rats to induce antigenic changes similar to those which occur during mammalian infection....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Toxin Mechanisms and Immunotoxins
• Share to Vector-borne infectious diseases
• Share to Viral Infections and Vectors