Article
Neurotrophic factors and the maldevelopmental hypothesis of schizophrenic psychoses. Review article.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 1998
Thome J, Foley P, Riederer P
Abstract excerpt
The maldevelopmental model of schizophrenia postulates pathological alterations in embryonal neurogenesis as the etiopathogenetic basis of schizophrenic psychosis; the neurotrophic factor hypothesis explains these changes as the result of disturbances of processes involving the trophic factors. Neurotransmitter deficits are thereby interpreted as epiphenomena of underlying neurotrophic factor deficacy. The...
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