Article
Genetic analysis of meiotic recombination in humans by use of sperm typing: reduced recombination within a heterozygous paracentric inversion of chromosome 9q32-q34.3.
American journal of human genetics - 1 Jun 1998
Brown G M, Leversha M, Hulten M, Ferguson-Smith M A, Affara N A, Furlong R A
Abstract excerpt
To investigate patterns of genetic recombination within a heterozygous paracentric inversion of chromosome 9 (46XY inv[9] [q32q34.3]), we performed sperm typing using a series of polymorphic microsatellite markers spanning the inversion region. For comparison, two donors with cytogenetically norm...
Topics
- Adult
- Case-Control Studies
- Chromosome Inversion
- Chromosomes, Human, Pair 9
- Genetic Variation
- Heterozygote
- Humans
- Male
- Meiosis
- Microsatellite Repeats
- Recombination, Genetic
- Spermatozoa