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Article

Carrier status for steroid 21-hydroxylase deficiency is only one factor in the variable phenotype of acne.

Clinical endocrinology - 1 Feb 1998

Ostlere L S, Rumsby G, Holownia P, Jacobs H S, Rustin M H, Honour J W

Abstract excerpt

OBJECTIVE: Previous endocrine studies of women with acne have produced diverse results. This study was designed to seek evidence, from endocrine and genetic studies, for impaired steroid biosynthesis in patients with acne. DESIGN: Adrenal stimulation tests with synthetic adrenocorticotrophic hormone (ACTH) were performed. MEASUREMENTS: Steroid hormones were measured basally and 30 minutes after ACTH. The results...

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Share to Adrenal Hyperplasia, Congenital

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9579234
DOI: 10.1046/j.1365-2265.1998.3811205.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Carrier status for steroid 21-hydroxylase deficiency is only one factor in the variable phenotype of acne.PMID 9579234Read ↗

Molecular abnormalities of the 21-hydroxylase gene in hyperandrogenic women with an exaggerated 17-hydroxyprogesterone response to short-term adrenal stimulation.Semantic proximity Read ↗

Clinical and molecular characterization of a cohort of 161 unrelated women with nonclassical congenital adrenal hyperplasia due to 21-hydroxylase deficiency and 330 family members.Semantic proximity Read ↗

Adrenal 21-hydroxylase gene mutations in Slovenian hyperandrogenic women: evaluation of corticotrophin stimulation and HLA polymorphisms in screening for carrier status.Semantic proximity Read ↗

Variable ACTH-stimulated 17-hydroxyprogesterone values in 21-hydroxylase deficiency carriers are not related to the different CYP21 gene mutations.Semantic proximity Read ↗

The spectrum of clinical, hormonal and molecular findings in 280 individuals with nonclassical congenital adrenal hyperplasia caused by mutations of the CYP21A2 gene.Semantic proximity Read ↗

Genetic defects of the CYP21A2 gene in girls with premature adrenarche.Semantic proximity Read ↗

Hyperandrogenism in carriers of CYP21 mutations: the role of genotype.Semantic proximity Read ↗

Genotype-phenotype analysis in late onset 21-hydroxylase deficiency in comparison to the classical forms.Semantic proximity Read ↗

Evidence for a heterozygote advantage in congenital adrenal hyperplasia due to 21-hydroxylase deficiency.Semantic proximity Read ↗

Congenital adrenal hyperplasia: 21-hydroxylase deficiency in the newborn and during infancy.Semantic proximity Read ↗

17-Hydroxyprogesterone in children, adolescents and adults.Semantic proximity Read ↗

Decreased cortisol secretion in nonclassical 21-hydroxylase deficiency before and during glucocorticoid therapy.Semantic proximity Read ↗

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