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Vaccine-Induced, Pseudorabies Virus-Specific, Extrathymic CD4 + CD8 + Memory T-Helper Cells in Swine

1 Jun 1998

Abstract excerpt

Pseudorabies virus (PRV; suid herpesvirus 1) infection causes heavy economic losses in the pig industry. Therefore, vaccination with live attenuated viruses is practiced in many countries. This vaccination was demonstrated to induce extrathymic virus-specific memory CD4+CD8+ T lymphocytes. Due to their major histocompatibility complex (MHC) class II-restricted proliferation, it is generally believed that these T...

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PMID: 9573253
DOI: 10.1128/jvi.72.6.4866-4873.1998

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