Article
Type specific and genotype cross reactive B epitopes of the L1 protein of HPV16 defined by a panel of monoclonal antibodies.
Virology - 10 Apr 1998
Kulski J K, Sadleir J W, Kelsall S R, Cicchini M S, Shellam G, Peng S W, Qi Y M, Galloway D A, Zhou J, Frazer I H
Abstract excerpt
Mouse monoclonal antibodies (mAbs) were raised against the major capsid protein, L1, of human papillomavirus type 16 (HPV16), produced in Escherichia coli with the expression plasmid pTrcL1. Epitope specificity could be assigned to 11 of these 12 antibodies using a series of linear peptides and fusion proteins from HPV16. One mAb (MC53) recognized a novel linear epitope that appears to be unique to the HPV16...
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