Article
[Molecular genetics of epithelial ovarian neoplasms: correlations with phenotype and biological behavior].
Der Pathologe - 1 Feb 1998
Diebold J
Abstract excerpt
The phenotypic variability of epithelial ovarian neoplasms correlates with a diversity of changes on the molecular level. Invasive serous and undifferentiated ovarian carcinomas are characterized by p53 mutations, extensive loss of genetic material of chromosome 17 and complex changes on many other chromosomes. These alterations are seen only in a minority of mucinous and endometrioid carcinomas, mainly in...
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