Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common ancestral mutation in the MEN1 gene is likely responsible for the prolactinoma variant of MEN1 (MEN1Burin) in four kindreds from Newfoundland.

Human mutation - 1 Jan 1998

Olufemi S E, Green J S, Manickam P, Guru S C, Agarwal S K, Kester M B, Dong Q, Burns A L, Spiegel A M, Marx S J, Collins F S, Chandrasekharappa S C

Abstract excerpt

Familial multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder with affected individuals developing parathyroid, gastrointestinal (GI) endocrine, and anterior pituitary tumors. Four large kindreds from the Burin peninsula/Fortune Bay area of Newfoundland with prominent features of prolactinomas, carcinoids, and parathyroid tumors (referred to as MEN1Burin) have been described, and they show...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Base Sequence

Share to Genetic Linkage

Share to Genetic Markers

Share to Molecular Sequence Data

Share to Pedigree

Source

Identifiers

PMID: 9554741
DOI: 10.1002/(SICI)1098-1004(1998)11:4<264::AID-HUMU2>3.0.CO;2-V

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common ancestral mutation in the MEN1 gene is likely responsible for the prolactinoma variant of MEN1 (MEN1Burin) in four kindreds from Newfoundland.PMID 9554741Read ↗

Multiple endocrine neoplasia type 1 variant with frequent prolactinoma and rare gastrinoma.Semantic proximity Read ↗

The MEN1 gene and pituitary tumours.Semantic proximity Read ↗

Germline MEN1 mutations in sixteen Japanese families with multiple endocrine neoplasia type 1 (MEN1).Semantic proximity Read ↗

Analysis of MEN1 c.482G>A (p.Gly161Asp) mutation in a pedigree with familial multiple endocrine neoplasia type 1.Semantic proximity Read ↗

Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related statesSemantic proximity Read ↗

A large Turkish pedigree with multiple endocrine neoplasia type 1 syndrome carrying a rare mutation: c.1680_1683 del TGAG.Semantic proximity Read ↗

Phenotype and genotype of patients with multiple endocrine neoplasia type 1 studied in Argentina.Semantic proximity Read ↗

Multiple endocrine neoplasia type 1 in Brazil: MEN1 founding mutation, clinical features, and bone mineral density profileSemantic proximity Read ↗

A novel germline mutation of multiple endocrine neoplasia type 1 (MEN1) gene in a Japanese MEN1 patient and her daughter.Semantic proximity Read ↗

Mutation analysis of the MEN1 gene in Belgian patients with multiple endocrine neoplasia type 1 and related diseasesSemantic proximity Read ↗

Five novel mutations in the familial multiple endocrine neoplasia type 1 (MEN1) gene. Mutations in brief no. 188. Online.Semantic proximity Read ↗

Characteristics of the Danish families with multiple endocrine neoplasia type 1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.