Article
Cutaneous tumors in patients with multiple endocrine neoplasia type 1 show allelic deletion of the MEN1 gene.
The Journal of investigative dermatology - 1 Apr 1998
Pack S, Turner M L, Zhuang Z, Vortmeyer A O, Böni R, Skarulis M, Marx S J, Darling T N
Abstract excerpt
Multiple endocrine neoplasia type 1 (MEN1), the heritable tendency to develop tumors of the parathyroid, pituitary, and entero-pancreatic endocrine tissues, is the consequence of a germline mutation in the MEN1 gene. Endocrine tumors in these patients result when the mutant MEN1 allele is accompa...
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