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Article

Selection with recurrent backcrossing to develop congenic lines for quantitative trait loci analysis.

Genetics - 1 Mar 1998

Hill W G

Abstract excerpt

SEWALL WRIGHT suggested that genes of large effect on a quantitative trait could be isolated by recurrent backcrossing with selection on the trait. Loci [quantitative trait loci (QTL)] at which the recurrent and nonrecurrent lines have genes of different large effect on the trait would remain segregating, while other loci would become fixed for the gene carried by the recurrent parent. If the recurrent line is...

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Identifiers

PMID: 9539447
DOI: 10.1093/genetics/148.3.1341
PMCID: PMC1460042

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