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Article

M Protein of the Group AStreptococcusBinds to the Seventh Short Consensus Repeat of Human Complement Factor H

1 Apr 1998

Abstract excerpt

Streptococcus pyogenes evades complement by binding the complement-regulatory protein factor H (fH) via the central conserved C-repeat region of M protein. However, the corresponding binding region within fH has not previously been precisely localized. fH is composed of 20 conserved modules called short consensus repeats (SCRs), each of which contains approximately 60 amino acids. A series of fH truncated and...

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Identifiers

PMID: 9529063
DOI: 10.1128/iai.66.4.1427-1431.1998

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M Protein of the Group AStreptococcusBinds to the Seventh Short Consensus Repeat of Human Complement Factor HPMID 9529063Read ↗

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