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Article

Insulin-like growth factor-binding protein-5 is cleaved by physiological concentrations of thrombin.

Endocrinology - 1 Apr 1998

Zheng B, Clarke J B, Busby W H, Duan C, Clemmons D R

Abstract excerpt

Insulin-like growth factor (IGF)-binding protein-5 (IGFBP-5) is cleaved by a serine protease that is secreted by fibroblasts and porcine smooth muscle cells (pSMC) in culture. To investigate whether other serine proteases could cleave this substrate at physiologically relevant concentrations, we...

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Identifiers

PMID: 9528953
DOI: 10.1210/endo.139.4.5945

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9528953-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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