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Article

A novel erythromycin resistance methylase gene (ermTR) in Streptococcus pyogenes.

Antimicrobial agents and chemotherapy - 1 Feb 1998

Seppälä H, Skurnik M, Soini H, Roberts M C, Huovinen P

Abstract excerpt

Erythromycin resistance among streptococci is commonly due to target site modification by an rRNA-methylating enzyme, which results in coresistance to macrolide, lincosamide, and streptogramin B antibiotics (MLSB resistance). Genes belonging to the ermAM (ermB) gene class are the only erythromycin resistance methylase (erm) genes in Streptococcus pyogenes with MLSB resistance that have been sequenced so far. We...

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Identifiers

PMID: 9527769
DOI: 10.1128/AAC.42.2.257
PMCID: PMC105397

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