Article
A novel erythromycin resistance methylase gene (ermTR) in Streptococcus pyogenes.
Antimicrobial agents and chemotherapy - 1 Feb 1998
Seppälä H, Skurnik M, Soini H, Roberts M C, Huovinen P
Abstract excerpt
Erythromycin resistance among streptococci is commonly due to target site modification by an rRNA-methylating enzyme, which results in coresistance to macrolide, lincosamide, and streptogramin B antibiotics (MLSB resistance). Genes belonging to the ermAM (ermB) gene class are the only erythromyci...
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