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Novel macrolide-lincosamide-streptogramin B resistance gene erm (56) in Trueperella pyogenes

7 Jul 2023

Abstract excerpt

ABSTRACT Whole-genome sequence analysis of a macrolide, lincosamide, streptogramin B (MLS B )-resistant Trueperella pyogenes from a dog revealed a new 23S ribosomal RNA methylase gene erm (56). Expression of the cloned erm (56) confers resistance to MLS B in T. pyogenes and Escherichia coli . The erm (56) gene was flanked by two IS 6100 integrated on the chromosome next to a sul1 -containing class 1 integron....

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PMID: 37417762
DOI: 10.1128/msphere.00239-23

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