Article
Lymphocyte apoptosis during classical swine fever: implication of activation-induced cell death.
Journal of virology - 1 Mar 1998
Summerfield A, Knötig S M, McCullough K C
Abstract excerpt
Infection of pigs with classical swine fever virus (CSFV), a member of the Flaviviridae family, causes a severe leukopenia, particularly notable with the lymphocytes. The goal of this study was to analyze mechanisms behind this CSFV-induced lymphopenia. To this end, the kinetics of leukocyte depletion, the appearance of apoptotic cells, and virus infection of leukocytes after infection of pigs with the virulent...
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