Haplotype HLA-B8-DR3 confers susceptibility to hepatitis C virus-related mixed cryoglobulinemia.

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Article

Haplotype HLA-B8-DR3 confers susceptibility to hepatitis C virus-related mixed cryoglobulinemia.

Blood - 15 Mar 1998

Lenzi M, Frisoni M, Mantovani V, Ricci P, Muratori L, Francesconi R, Cuccia M, Ferri S, Bianchi F B

Abstract excerpt

Our aim was to investigate whether host genetic factors are involved in the onset of hepatitis C virus (HCV)-related mixed cryoglobulinemia (MC). We studied 25 consecutive patients presenting with a full-blown clinical picture of MC by physical examination, blood chemistry, assessment of cryoglob...

Topics

Adult
Aged
Alleles
Autoimmune Diseases
Cryoglobulinemia
Disease Susceptibility
Female
Gene Frequency
Genes, MHC Class II
Genotype
HLA-B8 Antigen
HLA-DR3 Antigen
Haplotypes
Hepacivirus
Hepatitis C
Hepatitis, Chronic
Humans
Immunoglobulin M

Source

Open in PubMed

Identifiers

PMID: 9490691

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9490691-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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