Article
HLA DR-DQ combination associated with the increased risk of developing human HCV positive non-Hodgkin's lymphoma is related to the type II mixed cryoglobulinemia.
Tissue antigens - 1 Feb 2010
De Re V, Caggiari L, Monti G, Libra M, Spina M, Dolcetti R, De Zorzi M, Racanelli V, Crovatto M, Toffoli G
Abstract excerpt
This investigation was focused on the contribution of individual human leukocyte antigen (HLA)-DR and -DQ alleles to the human hepatitis C virus (HCV)(+) non-Hodgkin's lymphoma (NHL), with and without mixed cryoglobulinemia (MC), to study whether individual HLA class II alleles are expressed preferentially or equally in human HCV-specific NHL. For this purpose, peripheral blood mononuclear cells were obtained...
Topics
- Alleles
- Cryoglobulinemia
- HLA-DQ Antigens
- HLA-DR Antigens
- HLA-DRB1 Chains
- Hepacivirus
- Histocompatibility Antigens Class II
- Humans
- Lymphoma, Non-Hodgkin
- Risk