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A mutation in the Rho1-GAP-encoding gene BEM2 of Saccharomyces cerevisiae affects morphogenesis and cell wall functionality.

Microbiology (Reading, England) - 1 Jan 1998

Cid Víctor J, Cenamor Rosa, Sánchez Miguel, Nombela César

Abstract excerpt

Saccharomyces cerevisiae strain V918 was previously isolated in a search for thermosensitive autolytic mutants and found to bear a recessive mutation that caused the development of multinucleate swollen cells undergoing cell lysis. The BEM2 gene has been isolated by complementation of the phenotype of a V918 segregant. BEM2 encodes a Rho-GTPase-activating protein (GAP) which is thought to act as a modulator of...

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PMID: 9467898
DOI: 10.1099/00221287-144-1-25

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