Article
Polymerase chain reaction-based microsatellite analysis of fine-needle aspirations from Hürthle cell neoplasms.
Thyroid : official journal of the American Thyroid Association - 1 Dec 1997
Takiyama Y, Saji M, Clark D P, Phillips G S, Segev D L, Smallridge R C, Westra W H, Udelsman R, Zeiger M A
Abstract excerpt
Fine-needle aspiration (FNA) of the thyroid is the sine qua non in the preoperative evaluation of thyroid nodules. Despite this, cytological examination of FNA cannot differentiate malignant from benign Hürthle cell neoplasms. We have previously shown that Hürthle cell carcinomas harbor more genetic alterations on chromosomal arms 1q and 2p than Hürthle cell adenomas, and that all Hürthle cell neoplasms have a...
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