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Article

Localization of the giant axonal neuropathy gene to chromosome 16q24.

Annals of neurology - 1 Jan 1998

Flanigan K M, Crawford T O, Griffin J W, Goebel H H, Kohlschütter A, Ranells J, Camfield P R, Ptácek L J

Abstract excerpt

Giant axonal neuropathy (GAN) is a degenerative disorder of the peripheral nerves that is inherited as an autosomal recessive trait, presenting in early childhood and progressing to death, usually by late adolescence. Diagnosis is made by peripheral nerve biopsy, in which a striking pathological finding is seen--fibers distorted by giant axonal swellings filled with densely packed bundles of neurofilaments (the...

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Identifiers

PMID: 9450783
DOI: 10.1002/ana.410430126

Genes

GAN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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