Article
DNA variation and the future of human genetics.
Nature biotechnology - 1 Jan 1998
Schafer A J, Hawkins J R
Abstract excerpt
The use of DNA variants in the mapping of the human genome and in the positional cloning of monogenic disease genes is well established. Determining the genetic bases of the more common "multifactorial" diseases, however, presents a major challenge. The genetics of these diseases are complicated by the interplay between many genes and the environment. These investigations will require large numbers of DNA markers...
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