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Article

Allelic variations in the human growth hormone-1 gene promoter of growth hormone-deficient patients and normal controls.

European journal of endocrinology - 1 Nov 1997

Wagner J K, Eblé A, Cogan J D, Prince M A, Phillips J A, Mullis P E

Abstract excerpt

OBJECTIVE: Isolated growth hormone deficiency (IGHD) type IB is suggested to be more probably due to alterations in the genes directly involved in the hypothalamo-pituitary axis and/or in the specific transcriptional regulation (cis-trans coupling) of the hGH-1 gene than to alterations in the gene itself. In this study we analyzed the hGH-1 gene promoter region for structural alterations and allelic variations....

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Source

Identifiers

PMID: 9405026
DOI: 10.1530/eje.0.1370474

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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