Article
Characterization and sensitivity to interleukin 2 and interferon alpha of leukemic cells from a patient with large granular lymphocytic leukemia associated with chronic active Epstein-Barr virus infection.
Leukemia research - 1 Oct 1997
Toba K, Koike T, Takahashi M, Kishi K, Hashimoto S, Takahashi H, Uesugi Y, Ishikawa T, Aoki S, Maeo S, Naito M, Aizawa Y, Shibata A
Abstract excerpt
A patient presented with chronic large granular lymphocyte leukemia associated with chronic active Epstein-Barr virus infection (CAEBV). Cell cycle analysis revealed a minimal growth compatible with chronic lymphocytic leukemia After 5 months of treatment, the patient died from acute transformation of the leukemia. Cell harvested during chronic phase were analyzed for sensitivity to interleukin 2 (IL-2) and...
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