Article
A new mutation in the type II hair cortex keratin hHb1 involved in the inherited hair disorder monilethrix.
Human genetics - 1 Dec 1997
Winter H, Rogers M A, Gebhardt M, Wollina U, Boxall L, Chitayat D, Babul-Hirji R, Stevens H P, Zlotogorski A, Schweizer J
Abstract excerpt
Monilethrix is a rare dominant hair disease characterized by beaded or moniliform hair which results from the periodic thinning of the hair shaft and shows a high propensity to excess weathering and fracturing. Several cases of monilethrix have been linked to the type II keratin gene cluster on c...
Topics
- Amino Acid Sequence
- Base Sequence
- Female
- Germany
- Hair
- Hair Diseases
- Humans
- Keratins
- Male
- Molecular Sequence Data
- Mutation
- Pedigree
- Polymerase Chain Reaction