The association of HLA-DRB genes and the shared epitope with rheumatoid arthritis in Pakistan.

doi:10.1093/rheumatology/36.11.1184

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Article

The association of HLA-DRB genes and the shared epitope with rheumatoid arthritis in Pakistan.

British journal of rheumatology - 1 Nov 1997

Hameed K, Bowman S, Kondeatis E, Vaughan R, Gibson T

Abstract excerpt

The association of particular HLA-DR alleles and the shared epitope with rheumatoid arthritis (RA) is now well established. The strength of these links varies between races. Furthermore, the proposition that the presence of the shared epitope is indicative of severe disease has been more difficul...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Alleles
Arthritis, Rheumatoid
DNA
Epitopes
Female
Gene Frequency
Genotype
HLA-DR Antigens
HLA-DRB1 Chains
Humans
Male
Middle Aged
Oligonucleotide Probes
Pakistan

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