Article
The safety and efficacy of adefovir dipivoxil, a novel anti-human immunodeficiency virus (HIV) therapy, in HIV-infected adults: a randomized, double-blind, placebo-controlled trial.
The Journal of infectious diseases - 1 Dec 1997
Deeks S G, Collier A, Lalezari J, Pavia A, Rodrigue D, Drew W L, Toole J, Jaffe H S, Mulato A S, Lamy P D, Li W, Cherrington J M, Hellmann N, Kahn J
Abstract excerpt
Adefovir dipivoxil is a novel nucleotide analogue with several promising in vitro anti-human immunodeficiency virus (HIV) characteristics. To evaluate the safety and efficacy of adefovir dipivoxil monotherapy, a randomized, double-blind, placebo-controlled study was initiated involving 72 subjects with moderately advanced HIV disease. Subjects were randomly assigned in a 2:1 ratio to receive adefovir dipivoxil or...
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