Article
Association analysis of a regulatory variation of the serotonin transporter gene with severe alcohol dependence.
Alcoholism, clinical and experimental research - 1 Nov 1997
Sander T, Harms H, Lesch K P, Dufeu P, Kuhn S, Hoehe M, Rommelspacher H, Schmidt L G
Abstract excerpt
The present study tested the hypothesis that the short, low activity variant of a biallelic polymorphism in the 5' regulatory region of the human serotonin transporter (5-HTT) gene confers susceptibility to severe alcohol dependence marked by severe withdrawal symptoms. Applying a phenotype-genotype strategy, our population-based association analysis included 216 German controls and an extreme sample of 103...
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