Article
Identification of shuA, the gene encoding the heme receptor of Shigella dysenteriae, and analysis of invasion and intracellular multiplication of a shuA mutant.
Infection and immunity - 1 Dec 1997
Mills M, Payne S M
Abstract excerpt
shuA encodes a 70-kDa outer membrane heme receptor in Shigella dysenteriae. Analysis of the shuA DNA sequence indicates that this gene encodes a protein with homology to TonB-dependent receptors of gram-negative bacteria. Transport of heme by the ShuA protein requires TonB and its accessory proteins ExbB and ExbD. The shuA DNA sequence contains a putative Fur box overlapping the -10 region of a potential shuA...
Topics
- Amino Acid Sequence
- Bacterial Outer Membrane Proteins
- Base Sequence
- Cell Line
- Dysentery, Bacillary
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Humans
- Molecular Sequence Data
- Mutation
- Receptors, Cell Surface
- Shigella dysenteriae