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Article

Flow cytometric measurement of low density lipoprotein receptor activity validated by DNA analysis in diagnosing heterozygous familial hypercholesterolemia.

Cytometry - 15 Oct 1997

Urdal P, Leren T P, Tonstad S, Lund P K, Ose L

Abstract excerpt

We have evaluated whether low density lipoprotein (LDL) receptor activity of stimulated lymphocytes, as measured by an improved flow cytometric assay, may be used to diagnose familial hypercholesterolemia (FH). Cells were isolated from 75 children suspected from strict clinical criteria to be FH...

Topics

Child
Cholesterol
DNA
Female
Flow Cytometry
Genetic Carrier Screening
Humans
Hyperlipoproteinemia Type II
Leukocytes, Mononuclear
Lymphocyte Activation
Male
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, LDL

Source

Identifiers

PMID: 9383100

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9383100-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Flow cytometric measurement of low density lipoprotein receptor activity validated by DNA analysis in diagnosing heterozygous familial hypercholesterolemia.PMID 9383100Read ↗

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