Article
Natural history and determinants of clinical severity of sickle cell disease.
Current opinion in hematology - 1 Mar 1995
Serjeant G R
Abstract excerpt
Some of the factors determining the extremely variable clinical course of homozygous sickle cell disease are being identified. Genetic factors include alpha-thalassemia, beta-globin gene haplotypes, heterocellular hereditary persistence of fetal hemoglobin, and high total hemoglobin. Other factor...
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