Article
Rapid decline of fitness in panmictic populations of Drosophila melanogaster maintained under relaxed natural selection.
Proceedings of the National Academy of Sciences of the United States of America - 25 Nov 1997
Shabalina S A, Yampolsky LYu, Kondrashov A S
Abstract excerpt
The parameters of the spontaneous deleterious mutation process remain poorly known, despite their importance. Here, we report the results of a mutation accumulation experiment performed on panmictic populations of Drosophila melanogaster without any genetic manipulations. Two experimental populations were kept for 30 generations under relaxed natural selection. Each generation, 100 pairs were formed randomly, and...
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