Article
Differential regulation of gastrulation and neuroectodermal gene expression by Snail in the Drosophila embryo.
Development (Cambridge, England) - 1 Oct 1997
Hemavathy K, Meng X, Ip Y T
Abstract excerpt
The initiation of mesoderm differentiation in the Drosophila embryo requires the gene products of twist and snail. In either mutant, the ventral cell invagination during gastrulation is blocked and no mesoderm-derived tissue is formed. One of the functions of Snail is to repress neuroectodermal genes and restrict their expressions to the lateral regions. The derepression of the neuroectodermal genes into the...
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