Article
Genetic association study between pathological gambling and a functional DNA polymorphism at the D4 receptor gene.
Pharmacogenetics - 1 Oct 1997
Pérez de Castro I, Ibáñez A, Torres P, Sáiz-Ruiz J, Fernández-Piqueras J
Abstract excerpt
A Spanish sample consisting of 68 Caucasian pathological gambling patients (47 males and 21 females) and 68 unaffected controls were screened by the molecular analysis of a functional DNA polymorphism in the locus for the D4 dopamine receptor gene. Our results are consistent with the existence of a significant association between genetic variants at a DRD4 gene polymorphism and pathological gambling (chi 2 =...
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