Article
Molecular genetics of craniosynostotic syndromes.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1 Sept 1997
Müller U, Steinberger D, Kunze S
Abstract excerpt
This article reviews recent molecular genetic findings in autosomal dominant craniosynostotic syndromes. A mutation in the homeotic gene MSX2 was the first genetic defect identified in an autosomal dominant primary craniosynostosis, i.e. in craniosynostosis type 2 (Boston type). In the more commo...
Topics
- Animals
- Craniosynostoses
- DNA-Binding Proteins
- Homeodomain Proteins
- Humans
- Molecular Biology
- Mutation
- Receptors, Fibroblast Growth Factor
- Syndrome