Article
Phenotypic alterations in circulating monocytes induced by open heart surgery using heparinized and nonheparinized cardiopulmonary bypass systems.
Artificial organs - 1 Oct 1997
Ljunghusen O, Cederholm I, Lundahl J, Nilsson B, Olin C, Sjögren F, Stendahl O
Abstract excerpt
In this study of 31 patients with coronary bypass surgery, we used flow cytometry to compare heparin-coated and noncoated cardiopulmonary bypass systems on leukocyte activation. We found significant differences between the groups during bypass, with activation of the complement system, measured a...
Topics
- Adult
- Aged
- Anaphylatoxins
- Cardiopulmonary Bypass
- Complement Activation
- Complement C3a
- Female
- Fibrinolytic Agents
- Flow Cytometry
- Gene Expression Regulation
- Granulocytes
- HLA-DR Antigens
- Heparin
- Humans
- L-Selectin